Search results for "TRNA processing"

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Basic phenotypic analysis of six novel yeast genes reveals two essential genes and one which affects the growth rate

1999

Phenotypic analysis was performed on six mutants of Saccharomyces cerevisiae deleted in one of the following open reading frames (ORFs), located on chromosome II: YBR254c, YBR255w, YBR257w, YBR258c, YBR259w and YBR266c. Disruption of the ORFs was carried out in the diploid strain FY1679 using the kanMX4 marker flanked by short sequences homologous to the target locus. Tetrad analysis following sporulation of the heterozygous disruptants showed that YBR254c and YBR257w are essential genes. YBR257w was later characterized and renamed POP4, its gene product being involved in 5.8S rRNA and tRNA processing (Chu et al., 1997). The tetrad analysis performed for the heterozygous disruptant for YBR2…

Genetic MarkersGeneticsGenes FungalMutantSaccharomyces cerevisiaeTRNA processingBioengineeringLocus (genetics)Saccharomyces cerevisiaeBiologybiology.organism_classificationPolymerase Chain ReactionApplied Microbiology and BiotechnologyBiochemistryComplementationOpen Reading FramesOpen reading framePhenotypeGeneticsChromosomes FungalORFSGeneGene DeletionBiotechnologyYeast

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